Opportunity Information: Apply for PAR 22 137
The National Institutes of Health (NIH) funding opportunity "Accelerating the Pace of Child Health Research Using Existing Data from the Adolescent Brain Cognitive Development (ABCD) Study (R01-Clinical Trial Not Allowed)" (Funding Opportunity Number: PAR-22-137) supports research projects that use already-collected data from the ABCD Study to answer important questions about child and adolescent health and development. Rather than funding new data collection or clinical trials, this program is set up to help researchers move faster by analyzing a large, publicly available dataset that is already being gathered and shared through the NIMH Data Archive. The overall goal is to increase scientific knowledge about how adolescents develop across multiple domains, including physical and mental health, cognition, substance use, cultural context, and environmental influences, alongside detailed measures of brain structure and function.
A central feature of this opportunity is the ABCD Study itself, which is following youth beginning at ages 9 to 10 and repeatedly assessing them over a 10-year period. Because the study is longitudinal, it allows researchers to examine change over time, identify early predictors of later outcomes, and explore how different biological, psychological, social, and environmental factors interact across adolescence. The dataset is designed to be broad and multidimensional, meaning applicants can propose analyses that connect mental health symptoms with cognitive performance, relate substance use trajectories to brain development, or investigate how family, school, neighborhood, culture, and other contextual variables shape developmental pathways. The FOA is essentially an invitation for investigators to leverage this rich resource to generate new findings more quickly than would be possible by starting new cohorts from scratch.
The award mechanism is an NIH R01 research project grant, and the notice explicitly states "Clinical Trial Not Allowed," which signals that the funded work should focus on secondary data analysis and related research activities rather than prospective interventional studies that meet the NIH definition of a clinical trial. In practical terms, competitive applications will typically center on clear, testable research questions that can be addressed using the ABCD public use data, with rigorous methods, transparent analytic plans, and strong justification for why the proposed analyses matter for understanding adolescent health and development. Since the data are housed in the NIMH Data Archive, projects should be feasible within the structure and content of that repository and aligned with responsible data use and privacy protections associated with secondary analysis of human participant data.
Eligibility for this opportunity is broad and includes many types of domestic organizations and, notably, certain non-U.S. entities as well. Eligible applicants include state, county, city, township, and special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized Native American tribal governments; tribal organizations that are not federally recognized; public housing authorities and Indian housing authorities; nonprofit organizations with or without 501(c)(3) status (as long as they are not institutions of higher education, where applicable); for-profit organizations other than small businesses; and small businesses. The FOA also highlights additional eligible applicant categories such as Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISI), Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), faith-based or community-based organizations, eligible federal agencies, regional organizations, U.S. territories or possessions, and non-domestic (non-U.S.) entities (foreign organizations). This wide eligibility is meant to encourage participation from diverse institutions and communities, including those that are often underrepresented in large-scale research funding.
In terms of administrative details, the opportunity is listed as a discretionary grant under NIH, with activity areas spanning environment and health, and it is associated with multiple CFDA numbers (93.113, 93.242, 93.273, 93.313), reflecting the involvement of NIH institutes and programs that support different aspects of health research. The FOA was created on March 15, 2022, and the original closing date provided is May 7, 2025. The source information does not specify an award ceiling or expected number of awards, which is common in NIH announcements where budgets and award counts can vary depending on scientific merit, available funds, and the scope of proposed projects.
Overall, this grant opportunity is geared toward researchers who can use the ABCD Study public use dataset to produce timely, high-impact insights into adolescent development. The emphasis is on accelerating discovery by taking advantage of an unusually comprehensive, longitudinal, and widely accessible resource. Applicants that are likely to be responsive include those proposing well-powered, methodologically strong analyses that clarify developmental mechanisms, identify risk and protective factors, and contribute to better understanding of adolescent health and mental health trajectories without initiating new clinical trial activities. For background and context on the dataset and study design, the FOA directs applicants to the ABCD Study website at www.abcdstudy.org and to data access and documentation through the NIMH Data Archive.Apply for PAR 22 137
- The National Institutes of Health in the environment, health sector is offering a public funding opportunity titled "Accelerating the Pace of Child Health Research Using Existing Data from the Adolescent Brain Cognitive Development (ABCD) Study (R01-Clinical Trial Not Allowed)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.113, 93.242, 93.273, 93.313.
- This funding opportunity was created on 2022-03-15.
- Applicants must submit their applications by 2025-05-07. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.
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