Opportunity Information: Apply for W81XWH 22 KCRP NIRA
The FY22 DoD Kidney Cancer Research Program (KCRP) Nurse-Initiated Research Award is a funding opportunity designed to support innovative, high-impact kidney cancer research that is led by nurses working in clinical practice and/or academic settings. The intent is to elevate nurse-driven ideas that can meaningfully advance kidney cancer care, survivorship, and patient outcomes, especially when the work is conducted in a multidisciplinary way with a nurse in a leading role. Applications are strongly encouraged to align with one of the program's FY22 KCRP Focus Areas; if they do not, applicants are expected to make a clear case that the proposed study tackles a critical unmet need in kidney cancer.
A central theme of this award is the value nurses bring to cancer research because of their frequent, direct contact with patients and families and their unique perspective on real-world care delivery. The program explicitly recognizes the growing role of D.N.P.- and Ph.D.-prepared nurses as nurse scientists who can bridge bedside experience, systems-level care challenges, and rigorous research methods. The award is framed as a way to generate evidence that improves best practices in kidney cancer patient care, while also making space for research on access to care, health equity and disparities, patient and caregiver communication and education, quality of life, and support systems. In practical terms, the program is looking for projects that can change what happens in clinics and health systems, not just add a small piece of incremental knowledge.
From a research design standpoint, proposals must be clearly feasible, with well-defined methods and an articulated plan for achieving the project aims. The announcement gives examples of the kinds of work it hopes to fund, such as building best-practice models that strengthen nursing support and patient care, evaluating short- and long-term effects of interventions on patients or care delivery, studying psychosocial issues faced by kidney cancer patients and their families or care-partners, and examining nursing practice challenges during medical crises (for example, COVID-19 disruptions, staffing shortages, or barriers to accessing therapies). Preliminary data are encouraged but not required; however, every application must include a strong scientific rationale and a well-formulated, testable hypothesis. Any preliminary results included should come from the PI and/or collaborators, and the application should document that the necessary resources to complete the work are in place. Importantly, at least the PI or a collaborating investigator must have experience in kidney cancer research, and at least the PI or one collaborator must have experience in kidney cancer patient care.
The program emphasizes impact as a primary review expectation. The research is expected to have a clear pathway to improving care for people living with kidney cancer, either in the near term or over a longer horizon, but it must go beyond a modest, incremental advance. Applicants are expected to specify who benefits (for example, particular kidney cancer patient populations or individuals at risk) and how the findings could translate into improved clinical practice, care processes, or outcomes.
A notable feature introduced for FY22 is the "Qualified Collaboration Option," which encourages applicants to leverage the Kidney Cancer Research Consortium (KCRC). The KCRC was created through a prior KCRP award to provide infrastructure for kidney cancer studies, including recruitment networks, established protocols, Common Data Elements, and data management procedures. Applicants who plan to use KCRC infrastructure must include a letter of collaboration from the KCRC that spells out what support will be provided and how it adds value to the government. More broadly, the opportunity strongly encourages collaborations between military or Veteran institutions and non-military partners, reflecting DoD interest in research that is relevant to Service members, military families, Veterans, and the general public.
Funding is provided through assistance agreements, meaning awards will be made as either grants or cooperative agreements depending on how involved the DoD expects to be during performance. If the agency anticipates no substantial involvement, the mechanism is a grant; if substantial involvement is anticipated (such as collaboration, participation, or intervention), it will be a cooperative agreement, with the specifics defined during negotiation along with the start date. For budgeting, the anticipated direct costs for the entire period of performance may not exceed $300,000. Programmatically, the DoD planned to allocate about $0.96 million total to fund approximately two awards. Awards were expected to be made no later than September 30, 2023, and (if funded with FY22 appropriations) funds would be available for use only within the federal availability window, expiring for use on September 30, 2028.
There are also important compliance and scope boundaries. Clinical trials are not allowed under this award (defined as prospectively assigning human subjects to one or more interventions to evaluate effects on outcomes). However, the program can support correlative studies or other projects that run alongside a clinical trial, as long as the proposed work itself does not constitute a prohibited clinical trial and does not directly support intervention clinical trial costs. If human subjects, human anatomical substances, or human cadavers are involved, projects must undergo DoD regulatory review through the USAMRDC Office of Research Protections, Human Research Protection Office (HRPO), in addition to local IRB or ethics review; local IRB approval is not required at submission, but applicants should plan for up to about three months for HRPO review after all required documents are submitted. Multi-site studies must include a plan for a single IRB arrangement and identify the lead institution responsible for the master protocol and consent. If animals are involved, there is an additional DoD review through ACURO on top of local IACUC, and applicants should expect a longer timeline (often three to four months) for that regulatory process. Finally, if the work requires access to active-duty populations or DoD or VA resources or databases, the application must describe the access plan at submission and how access will be maintained over the life of the project.
Overall, the FY22 KCRP Nurse-Initiated Research Award is aimed at nurse-led kidney cancer research with a clear, practice-changing payoff, a strong and feasible scientific plan, and appropriate kidney cancer expertise on the team, with optional (and encouraged) integration of established consortium infrastructure to strengthen recruitment, data standards, and execution.Apply for W81XWH 22 KCRP NIRA
- The Department of Defense, Dept. of the Army -- USAMRAA in the science and technology and other research and development sector is offering a public funding opportunity titled "DoD Kidney Cancer, Nurse-Initiated Research Award" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 12.420.
- This funding opportunity was created on Jun 15, 2022.
- Applicants must submit their applications by Oct 20, 2022. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The number of recipients for this funding is limited to 2 candidate(s).
- Eligible applicants include: Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled Additional Information on Eligibility.
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