Opportunity Information: Apply for RFA DA 22 052
The HEAL Initiative: HEAL Data2Action (HD2A) Data Infrastructure Support Center funding opportunity (RFA-DA-22-052) is a National Institutes of Health (NIH) cooperative agreement (U24; clinical trial optional) intended to establish one centralized Data Infrastructure Support Center for the HEAL Data-to-Action (D2A) Innovation Grants. The overall goal is to strengthen how D2A projects use real-world data to guide practical decisions, especially in communities responding to opioid-related harms. Rather than funding multiple centers, this announcement is designed to support a single, program-wide hub that can provide shared tools, expertise, and coordination so that local and regional D2A grantees can move faster from data to measurable action.
The Support Center is expected to focus on four main areas of work. First, it would provide tailored data infrastructure and hands-on resources to help Innovation Grant teams identify relevant existing records and data systems, combine or link those data sources, and analyze them in ways that help forecast service needs, identify gaps in care, and track whether new interventions are improving outcomes over time. This could involve advising on data linkage strategies, standardizing variables, strengthening analytic workflows, and supporting repeatable monitoring methods so that improvements can be seen and measured rather than assumed.
Second, the Center would help D2A grantees access key datasets that may be broadly useful across multiple projects. In practice, that means acting as a facilitator for shared data resources by helping projects understand what datasets exist, how to request or obtain them, what use restrictions apply, and how to structure agreements or processes so data can be used efficiently and appropriately. The emphasis is on reducing the friction that often slows down local data work, especially when datasets are spread across agencies or systems.
Third, the Support Center would provide data visualization support aimed at making local data more usable for decision-makers. Many public health and service-delivery choices depend on clear, timely information, so the Center would be positioned to help create dashboards, visual reports, and other communication tools that translate complex data into accessible insights. The intention is not just to produce charts, but to improve how local leaders, implementers, and partners understand trends, disparities, capacity constraints, and changes following implementation of new strategies.
Fourth, the Center would compile a library of measures that projects can use consistently across sites to track service delivery and outcomes, including measures aligned with concepts like the opioid care cascade. A shared measurement library can improve comparability across projects, support benchmarking, and reduce the burden on individual grantees to reinvent definitions and indicators. This also helps ensure that when projects report progress, they are speaking the same measurement language, which is important for program-level learning.
This FOA is one piece of a broader HEAL D2A program structure and is described as running in parallel with companion FOAs that support other D2A components. That parallel structure signals that the Support Center is meant to be deeply connected to, and responsive to the needs of, the Innovation Grants and other D2A activities, rather than operating as an isolated technical contractor. Because the funding instrument is a cooperative agreement, NIH typically expects substantial programmatic involvement, meaning the awardee would coordinate closely with NIH staff and align deliverables with evolving D2A program priorities.
Eligible applicants are broad and include many types of U.S.-based entities: state, county, and city or township governments; special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized Native American tribal governments; tribal organizations that are not federally recognized; public housing authorities/Indian housing authorities; nonprofits with or without 501(c)(3) status; for-profit organizations (other than small businesses); small businesses; and other eligible entities. The announcement also explicitly calls out additional eligible categories such as Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions, Hispanic-serving Institutions, Historically Black Colleges and Universities, Tribally Controlled Colleges and Universities, eligible federal agencies, faith-based or community-based organizations, regional organizations, and U.S. territories or possessions. At the same time, it clearly excludes non-domestic (non-U.S.) entities and foreign institutions, does not allow non-domestic components of U.S. organizations to apply, and prohibits foreign components as defined by the NIH Grants Policy Statement.
Key administrative details provided include an original closing date of March 10, 2022, and an award ceiling of $1,000,000. The listing includes CFDA numbers 93.213, 93.279, and 93.846, reflecting the NIH program authorities associated with this opportunity. Overall, the grant is best understood as an infrastructure-and-enablement award: it is designed to give the broader HEAL D2A Innovation Grants a shared backbone for data acquisition, integration, analytics, visualization, and standardized measurement so that local implementation work can be guided by stronger evidence and tracked with clearer, more consistent metrics.Apply for RFA DA 22 052
- The National Institutes of Health in the education, health sector is offering a public funding opportunity titled "HEAL Initiative: HEAL Data2Action (HD2A) Data Infrastructure Support Center (U24 Clinical Trial Optional)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.213, 93.279, 93.846.
- This funding opportunity was created on 2022-01-03.
- Applicants must submit their applications by 2022-03-10. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $1,000,000.00 in funding.
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.
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Frequently Asked Questions (FAQs): HEAL Data2Action (HD2A) Data Infrastructure Support Center (RFA-DA-22-052)
1. What is this funding opportunity?
This opportunity (RFA-DA-22-052) is an NIH cooperative agreement to establish a single centralized Data Infrastructure Support Center for the HEAL Data-to-Action (D2A) Innovation Grants. The Support Center is intended to serve as a program-wide hub that provides shared tools, expertise, and coordination so D2A projects can move faster from data to measurable action.
2. What is the overall purpose of the Support Center?
The overall goal is to strengthen how HEAL D2A projects use real-world data to guide practical decisions, particularly in communities responding to opioid-related harms. The Support Center is meant to enable local and regional D2A grantees by improving data acquisition, linkage, analysis, visualization, and measurement consistency across sites.
3. Is NIH planning to fund more than one Support Center?
No. This announcement is designed to support one centralized, program-wide Data Infrastructure Support Center rather than multiple centers.
4. What type of award mechanism is used?
The funding instrument is a cooperative agreement (U24), with clinical trial optional.
5. What does it mean that this is a cooperative agreement?
A cooperative agreement typically involves substantial NIH programmatic involvement. Based on the description provided, the awardee should expect to coordinate closely with NIH staff and align deliverables with evolving HEAL D2A program priorities.
6. Who is the Support Center intended to support?
The Support Center is intended to support the HEAL Data-to-Action (D2A) Innovation Grant teams and to operate in a way that is deeply connected to the broader D2A program structure, rather than functioning as an isolated technical contractor.
7. What are the four main areas of work the Support Center is expected to cover?
The Support Center is expected to focus on: (1) tailored data infrastructure and hands-on resources for identifying, combining/linking, and analyzing real-world data; (2) facilitating access to key datasets useful across multiple projects; (3) providing data visualization support (dashboards, visual reports, and communication tools); and (4) compiling a shared library of measures to promote consistent tracking of service delivery and outcomes across sites.
8. What kinds of data infrastructure support would be provided to Innovation Grant teams?
The Support Center would help teams identify relevant existing records and data systems, combine or link data sources, and analyze them to forecast service needs, identify gaps in care, and track whether interventions improve outcomes over time. Examples of support described include advising on data linkage strategies, standardizing variables, strengthening analytic workflows, and supporting repeatable monitoring methods.
9. How does this opportunity address data linkage and integration challenges?
The Support Center is expected to help projects combine or link data sources and to provide guidance on strategies and workflows that make linkage and integration more feasible and repeatable, including standardizing variables and improving analytic processes.
10. What does "help D2A grantees access key datasets" mean in practice?
It means the Support Center would act as a facilitator for shared data resources by helping projects understand what datasets exist, how to request or obtain them, what use restrictions apply, and how to structure agreements or processes so data can be used efficiently and appropriately.
11. Why is the Support Center focused on reducing friction in data access?
The opportunity emphasizes that local data work is often slowed when datasets are spread across agencies or systems. The Support Center is intended to reduce those delays by helping clarify availability, request pathways, restrictions, and appropriate processes for use.
12. What kind of visualization support is expected?
The Support Center would provide data visualization support aimed at making local data more usable for decision-makers. This includes dashboards, visual reports, and other communication tools that translate complex data into accessible insights that can inform public health and service-delivery decisions.
13. Is the visualization work only about creating charts?
No. The description emphasizes that the intention is not just to produce charts, but to improve how local leaders, implementers, and partners understand trends, disparities, capacity constraints, and changes following the implementation of new strategies.
14. What is the shared measures library, and why is it important?
The Support Center would compile a library of measures that projects can use consistently across sites to track service delivery and outcomes, including measures aligned with concepts like the opioid care cascade. This supports comparability, benchmarking, and reduces the burden on individual grantees to reinvent definitions and indicators.
15. How does a shared measurement library help the overall program?
Using consistent measures helps ensure projects report progress using the same measurement language, which supports program-level learning and makes cross-site comparisons more meaningful.
16. How does this FOA fit into the broader HEAL D2A program?
This FOA is described as one piece of a broader HEAL D2A program structure and is intended to run in parallel with companion FOAs that support other D2A components. The Support Center is meant to be responsive to Innovation Grants and other D2A activities.
17. What is the main focus area of the D2A projects this Support Center will enable?
The Support Center is meant to strengthen the use of real-world data to guide practical decisions, especially in communities responding to opioid-related harms, and to support tracking of outcomes and service delivery improvements over time.
18. What is the award ceiling listed for this opportunity?
The listing includes an award ceiling of $1,000,000.
19. What was the original closing date?
The original closing date listed is March 10, 2022.
20. What are the CFDA numbers associated with this opportunity?
The CFDA numbers listed are 93.213, 93.279, and 93.846.
21. Who is eligible to apply?
Eligibility is broad and includes many U.S.-based entity types, including state, county, city or township governments; special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized Native American tribal governments; tribal organizations that are not federally recognized; public housing authorities/Indian housing authorities; nonprofits with or without 501(c)(3) status; for-profit organizations (other than small businesses); small businesses; and other eligible entities.
22. Are specific institution categories explicitly highlighted as eligible?
Yes. The announcement explicitly calls out Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions, Hispanic-serving Institutions, Historically Black Colleges and Universities, Tribally Controlled Colleges and Universities, eligible federal agencies, faith-based or community-based organizations, regional organizations, and U.S. territories or possessions.
23. Are non-U.S. or foreign organizations eligible?
No. The opportunity excludes non-domestic (non-U.S.) entities and foreign institutions.
24. Can a U.S. organization apply if the work includes a non-domestic component?
No. The announcement states that non-domestic components of U.S. organizations are not allowed to apply.
25. Are foreign components allowed under this opportunity?
No. The opportunity prohibits foreign components as defined by the NIH Grants Policy Statement.
26. Is this award primarily intended to fund direct local interventions?
Based on the description provided, the grant is best understood as an infrastructure-and-enablement award. It is designed to provide a shared backbone for data acquisition, integration, analytics, visualization, and standardized measurement to support local implementation work rather than to function as a set of separate local intervention awards.
27. What does "real-world data" support look like in this context?
In this context, the Support Center would help D2A projects identify existing records and data systems, link and analyze data sources, and implement monitoring methods to forecast service needs, identify gaps in care, and track changes in outcomes over time.
28. What kind of outcomes tracking is envisioned?
The description emphasizes tracking whether new interventions are improving outcomes over time using repeatable monitoring methods and consistent measures, so improvements can be observed and measured rather than assumed.
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